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Description
It has been demonstrated that diurnal variation in circulating endothelial nitric oxide synthase (NOS3) levels, which regulate both endothelial functions, is established in healthy women, indicating that NOS3 may be another mediator of circadian rhythmregulated vessel formation [111, 112, 113]

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doi: 10.1038/onc.2016.521 224 XiZSiJNanJ

Beyond DAMPs, cytokines also contribute significantly
