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1) but had null associations with ischemic stroke (OR 1.02, 95% CI 0.98 to 1.05) and AF (OR 1.01, 95% CI 0.97 to 1.04) (Fig

In 2007, the Food and Agriculture Organization (FAO) of the United Nations estimated that the gross world production of grape berries was over 67 million tons per year, with land occupancy of 7,272,583 ha (FAO, 2007 [1])

As for other metabolic disorders associated with aberrant mitochondrial bioenergetics, pathogenic AIFM1 mutations cause a large spectrum of clinical outcomes, including fatal encephalomyopathy, ataxia, late-onset neuromyopathy, and mild deafness 8

Downregulation of acetyl-CoA synthetase 2 is a metabolic hallmark of tumor progression and aggressiveness in colorectal carcinoma

Alterations in mitochondrial DNA integrity, bioenergetic capacity, quality control systems, and redox homeostasis converge to create a network of cellular vulnerability that interfaces directly with innate immune signaling