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Mechanistically, AZM activates the sphingomyelin (SM) metabolic pathway, leading to reduced goblet cell proliferation and inhibition of Th2 cytokines, including IL-5 and IL-13, thereby attenuating type 2 airway inflammation (Huang et al., 2025)

The reaction mixture was stirred at 80C for 1.5 h and quenched with ice water and filtered

This redox interaction supports deactivation of CBC enzymes and activation of the first step of the oxidative pentose phosphate pathway, respectively, facilitating the tight regulation of plastid carbon metabolism in light to dark transitions to avoid futile cycling

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These findings support a beneficial effect of Pycnogenol on cognitive functions in elderly people