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Recent studies have revealed a type 1 immune-restricted promoter for the ST2 encoding gene Il1rl1 that is crucial for antiviral CD8+ cytotoxic T cell and CD4+ Th1 cell responses

Therefore, nitric oxide synthase inhibitors being developed for acute diseases may also be suitable to treat COPD

The oxaliplatin-resistant OVCAR8 cell line (OVCAR8/OxR) was generated by treating the OVCAR8 human ovarian cancer cell line repeatedly with increasing concentrations of oxaliplatin until at least a 10-fold increase in IC 50 was observed

Indeed, the downexpression of GLAST or GLT-1 increased extracellular glutamate levels in the CNS, while that of EAAC1 did not affect the levels [105]

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