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Description
Sequence and structure: WAGGDASGE nonapeptide DSIP is a linear nonapeptide of nine amino acids (one-letter code WAGGDASGE), molecular weight approximately 849 Da, with a sequence that is unusual in two respects
The endocrine axis is disrupted: chronic hypoxia suppresses gonadotropin release and T production, further exacerbating spermatogenic arrest
28 CasieriL.GallardoK.WipfD
Deficiency develops gradually, as the body stores approximately 2-5 mg of B12 in the liver, which can sustain normal function for several years even with inadequate intake or absorption
K.BalkwillD
