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Results A counter-selection system was engineered in Saccharomyces cerevisiae based on the known feedback inhibition of gamma-glutamylcysteine synthetase (GSH1) gene expression, which is rate limiting for GSH synthesis: the GSH1 ORF and the counter-selectable marker GAP1 were expressed under control of the TEF1 and GSH-regulated GSH1 promoters, respectively

Combining these technologies not only enhances the delivery and efficacy of existing treatments but also paves the way for new therapeutic modalities

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Alpha-lipoic acid is called the universal antioxidant for its ability to boost glutathione levels and potent antioxidant actions