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Another study [54] looking at those with neurodegenerative disorders found that a single intravenous dose of NAC led to an increase of the blood GSH/GSSG ratio and levels of glutathione in the brain

Interestingly, strains lacking Tsa1, Tsa2, both Srx1 and Cta1, and combinations lacking Cta1 and Tsa1 or Cta1 and Tsa2 showed a clear reduction in survival, with survival rates less than 50% compared to the parental strain (Figure 4) [68]

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The results of the study carried out by Adelekan & Thurnham ( Reference Adelekan and Thurnham 38 ) indicated that the mean erythrocyte GPx activity in riboflavin-deficient rats was slightly, but not significantly lower than that in the control rats