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The prevalence of cobalamin deficiency among vegetarians assessed by serum vitamin B12: a review of literature. European Journal of Clinical Nutrition 68(5) (2014): 541548

Proton pump inhibitors (acid blockers) and over-the-counter non-steroidal anti-inflammatory agents can change the environment of the GI tract predisposing to nutrient deficiencies Unfortunately, that isnt an exhaustive list, but it does give you a pretty good idea of why you should be concerned about your vitamin B12 levels

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[2] In the US, non-prescription products can be purchased providing up to 1,000 g each, and it is a common ingredient in energy drinks and energy shots, usually at many times the recommended dietary allowance of B 12