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[10] In EDS types I and II, cEDS and clEDS, causative mutations may involved the COL5A1, COL5A2, and tenascin-X genes and are implied to be in the COL1A2 gene

262 A parallel mechanism is observed in idiopathic pulmonary fibrosis (IPF), where telomere attrition in lung fibroblasts, combined with chronic inflammation and TGF- pathway activation, promotes excessive collagen deposition and irreversible structural damage

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It showed improvement in ocular surface hydration and reduced corneal staining scores, also preserved the integrity of corneal epithelial cells and reduced the inflammatory responses

Q2: Will it lighten my skin tone