what is melanotic macules macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in Mucosal melanocytic macules
Description
This also indicates possible receptor desensitization or compensatory mechanisms

Citicoline in the treatment of acute ischaemic stroke: an international, randomised, multicentre, placebo-controlled study (ICTUS trial)

Depression: a new animal model sensitive to antidepressant treatments

Significant differences were observed in the proportion of stage III melanosomes ( p = 2.575e-7, effect size r = 0.8358) and stage II melanosomes ( p = 1.568e-8, effect size r = -0.9054)

In a study conducted by The IAMS Company, overweight dogs were fed similar diets
