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Tan TM, Field BCT, McCullough KA, Troke RC, Chambers ES, Salem V, et al
Many hurdles for approval of devices remain including low mg loadings, potential to block the lumen of the GI tract with 000 size capsules, the possibility of gut wall perforation, an unclear regulatory pathway, and the question of whether patients will ultimately find these approaches acceptable
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& Taschler, U
Interestingly, there was no impact of residence time on empty capsid binding across the conditions tested (Figure 3B)
