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In ApoE / mice subjected to chronic mild stress, lipid metabolism disorders, increased adipocyte hypertrophy, and reduced PPARG gene expression promote AS, while PPARG exhibits an anti-ferroptosis effect (Mao et al., 2023)

This approach moves beyond symptomatic pain management to modulate the pain source itself (Figure 5)

However, clinical research on the application of nanoparticles for early lung cancer screening is lacking

Activation of NF-B promotes cancer progression by inducing various genes responsible for cancer cell survival, proliferation, and metastasis, and interacts with multiple cancer-associated pathways such as PI3K/Akt, AMPK, and MAPK (Li et al., 2024)

While histopathological diagnosis is regarded as the gold standard, the final report takes many days to become available [30]