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Eren Y, Dirik E, Neeliolu S, Erel

Updated April 19, 2021

This can result from the loss of GPX4 activity, as seen with (1S, 3R)-RAS-selective lethal 3 (RSL3), which irreversibly targets the selenocysteine residue in the active site of GPX4, 46 or through enhanced degradation, such as with FIN56, which reduces GPX4 abundance

Two types of cells were identified in rat seminiferous tubules: the Sertoli cells and the spermatogenic cells