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However, the interaction between PIEZO1-mediated ion channel activity and DOX-induced MQS impairment requires further systematic investigation

Moreover, ErbB receptors, particularly EGFR and ErbB2, are implicated in the induction of oxidative stress and subsequent cellular survival mechanisms

While significant challenges remain, the integration of deep mechanistic knowledge with cutting-edge biotechnologies has rendered the goal of a definitive cure not merely aspirational, but a tangible target within strategic reach