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J Intern Med 286(1):3240 Brydges CR et al (2021) Indoxyl sulfate, a gut microbiome-derived uremic toxin, is associated with psychic anxiety and its functional magnetic resonance imaging-based neurologic signature

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The delivery system not only improves the water solubility and bioavailability of sorafenib, but also increases the accumulation of the drug in the tumor site through an active targeting mechanism, thereby maintaining efficacy at lower doses and reducing toxic reactions (Table 2)

Cildir G, Low KC, Tergaonkar V

In view of the above research results, we intend to explore a ferroptosis-based anti-tumor therapy