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A limitation of the study was the small sample size and the lack of investigation into whether CAL02s efficacy is concentration-dependent

FXR activation in enterocytes induces FGF15/19, which activates fibroblast growth factor receptor 4 (FGFR4) on hepatocytes to stimulate regeneration
Murugesan, G

Mller N, et al

Primers 9:19