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Diverse occludin functions Unexpectedly, intestinal epithelial specific occludin knockout protects mice from experimental colitis and epithelial injury driven by intrinsic and extrinsic TNF signalling pathways

Bottom left: VX exerts toxicity through irreversible inhibition of acetylcholinesterase (AChE), causing accumulation of acetylcholine (ACh) at synapses and resulting in cholinergic overstimulation

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Front Immunol 13:934494 Zhao C et al (2025) Immunoadjuvant-functionalized metal-organic frameworks: synthesis and applications in tumor immune modulation

In aging, progressive mitochondrial dysfunction occurs due to the loss of the thioretinaco ozonide oxygen ATP complex from mitochondrial membranes through the opening of the mitochondrial permeability transition pore [65]