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Furthermore, their study revealed that splenectomy abrogates the neuroprotective efficacy of RIPreC in mice and reverses the beneficial shifts in peripheral blood immune cell composition ( Figure 2 )

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doi: 10.1038/s41366-022-01085-4

These proinflammatory molecules also induce the above lesions through the nuclear factor-B (NF-B), Janus kinase/signal transducers and activators of transcription (JAK/STAT), and TGF-/Smad signaling pathways[99-101]

Alcohol Consumption and Prevalence of Human Papillomavirus (HPV) Infection among US Men in the HPV in Men (HIM) Study