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The common denominator of the GPX family is the first redox centre comprising (seleno) Cys, Trp, Asn and Gln 15,16

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utilized CD38 KO mice and CD38 catalytically inactive mice to demonstrate that inhibiting CD38 improves NAD levels, exercise capacity, heart rate variability, and provides protection against catecholamine-induced ventricular arrhythmias [11]

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Thus, the natural progression of atopic disease from childhood into adulthood may underlie our inability to detect differences in plasma GPX activity in adults with and without non-EoE atopic disease

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Green Chem 26:70917100

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