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The treatment group had a significantly higher mean total lesion count maintenance rate from baseline to week 12 (56%) than the placebo group (36%) ( p = 0.021)


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Drusen Formation and the Role of Oxidative Stress in Their Development Drusen, extracellular deposits located between the RPE basal lamina and the Bruchs membrane inner collagenous layer, are believed to form when RPE cells fail to effectively store shed POS or degrade cellular debris [41]

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