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Acad Emerg Med

The rate constant for the fusion construct with dithiol PfGrx C88S was about three times smaller and decreased again fivefold for monothiol PfGrx C32S/C88S (Fig

These pathways involve key enzymes including S-methyl-5-thioadenosine phosphorylase (MTAP), methylthioribose-1-phosphate isomerase (MRI1), cystathionine beta-synthase (CBS), and cystathionine gamma-lyase (CTH) (Fig

10.1093/humrep/dew243 16 ChenH.NieP.LiJ.WuY.YaoB.YangY.et al (2024)

After that, in order to validate the model, we simulate the system of equations with the estimated parameter values and calculate goodness of fit of the [GSH] and [GSSG] simulation results to the validation set