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It also laid a theoretical foundation for our subsequent exploration of the mechanism by which GSTP1 may protect lung cancer cells and inhibit ferroptosis after tumor radiation therapy
Like NO, the effects of H 2 S are concentration-dependent - whereas, at lower concentrations, H 2 S may be protective, excessive H 2 S contributes to cytotoxicity, including inhibition of cytochrome C oxidase, halting mitochondrial respiration [24,309]
Moreover, ectopic expression of HDAC1/2/3 downregulated global histone succinylation and acetylation [24]
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