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For ALSFRS-R, a mean slope of 1.0 was observed in treated subjects compared to 1.4 in those not treated ( p = 0.0575)

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Thus, whilst phytanic acid has been implicated in the normal biological process of adipogenesis, further research is needed to elucidate its precise mechanisms of action and its role in adipose tissue biology including whether it is able to commit MSCs to the (WAT) adipocyte lineage, or rather promotes lipid accumulation and maturation in committed (pre-)adipocytes