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Conclusions and outlook This review summarizes the characteristics of iron metabolism in humans, the association between obesity and ferroptosis, and the neuroimmune regulation associated with obesity and ferroptosis
All of these factors are targeted in drug development in order to increase leptin sensitivity in obese individuals (Fig

Compared with traditional therapy modalities, nanoparticles improve the targeting efficiency of mitochondria, enhance the stability and bioavailability of therapeutics, and reduce the side effects on other non-target sites
10.1056/NEJMoa2103583 267 SongC.HiipakkaR
