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Similar to other GLP-1 drugs, CagriSema had mild to moderate side effects, which were mainly gastrointestinal (including nausea, vomiting, diarrhea, and constipation) and diminished over time
In the Billon 2023 paper, mice given 30 mg/kg IP still showed measurable plasma and muscle concentrations at 6 hours post-injection, which helps explain why twice-daily dosing was used in efficacy studies
vitamin B-12
