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These beneficial effects may be due to the formation of detour circuitswhich encompass spared tissue surrounding the lesionand could reconnect locomotor circuits [69], thus enabling afferent inputs to be processed and conveyed to the cortex [73] and improving spinal reflexes, even below the injury [74]

Conflict of interest The authors declare no competing interests

Without robust data, it is hard to distinguish hope from hype

Similarly, it is also safe for direct tissue contact due to the absence of any preservative or additive

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