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10.1038/s41598-018-26956-7 87 LiuM.LiL.ChuJ.ZhuB.ZhangQ.YinX.et al (2015)

Most researchers recommend cycling protocols (8-12 weeks on, 4 weeks off) rather than continuous indefinite use until more long-term data becomes available

Worthy of mention, a rise in the prevalence of subclinical autoimmune hypothyroidism and thyroid autoantibodies has been reported after iodine supplementation in iodine-deficient countries, likely in relation to enhanced immunogenicity of thyroglobulin [27]
Vitamin B12 might affect sleep in a distinct way for non-obese adults

doi:10.1006/bbrc.2001.4315
