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Others have shown that cellular oxidative stress contributes to dysregulation of both pro-oxidant (NOX enzymes) and anti-oxidant enzymes (catalase, superoxide dismutases, peroxiredoxins, and glutathione peroxidases) [47] and this could be seen in the neutrophil genomic changes in our study predominantly in redox-associated genes

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That is, even if a medical product receives a new FDA approval or clearance, it may not necessarily be considered new for purposes of new technology add-on payments if it is substantially similar to another medical product that was approved or cleared by FDA and has been on the market for more than 2 to 3 years

Moreover, a crucial advantage of placental tissue cultures concerns the intact microarchitecture, while parallelly ensuring the intercell and paracrine communications [41]