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To confirm the capacity of paclitaxel to bind specifically to the binding site of C5aR1 for its natural ligand C5a, we performed competition experiments using a monoclonal anti-C5aR1 antibody, which is known to neutralize the C5aR1 and C5a interaction (Fig

Altered lipid metabolism and autophagy also contribute to neurodegenerative diseases, such as Parkinsons disease (PD), a progressive disorder that affects movement

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Ann N Y Acad Sci 1025: 257266
