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For B12 to be absorbed properly, it must bind with a protein called "intrinsic factor," which is produced in the stomach
These efforts were spearheaded by US patient support groups that have urged the National Institutes of Health to fund research studies to better understand IC/BPS pathophysiology and to fund clinical studies to identify valid treatment approaches

Lack of vitamin B12 can cause a number of health problems, including muscular weakness, numbness, stiffness in the legs, and memory loss

10.1371/journal.pone.0134311 PLoS One

We talked about some of the outcomes and such
