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There is increasing evidence of peripheral and central immune system cross connectivity contributing to acceleration of a proinflammatory state in ALS [245]

This is a consequence of the simultaneous operation of the two trimethylammonium compound carriers, CaiT and ProU [6, 69] (Fig

Vitamin C is a cofactor for L-carnitine biosynthesis, but its implications appear controversial [17]

Ramser J, Ahearn ME, Lenski C, et al
