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However, drug efflux can be reduced through the use of BCRP inhibitors, such as gefitinib, a TKI that blocks BCRP transporter function, restoring drug sensitivity (263)

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Some years later total GST enzyme activity was measured in three barley cultivars inoculated with barley powdery mildew

Further examination of double mutants (Cla+Arr, Cla+W, and Arr+W), revealed that only Cla mutants exhibited a decrease in FRET efficiencies compared to WT (Cla+Arr: 5.25% and Cla+W: 5.93%)

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