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It is also used as an antidote to paracetamol (acetaminophen) poisoning and found to be effective for the prevention of car-diotoxicity by doxorubicin and hae norrhagic cystitis from oxazaphosphorines.After an oral dose of N-acetylcysteine 200 to 400mg the peak plasma concentration of 0.35 to 4 mg/L is achieved within 1 to 2 hours

References Marianne C Walsh, Lorraine Brennan, Estelle Pujos-Guillot, Jean-Louis Sbdio, Augustin Scalbert, Ails Fagan, Desmond G Higgins, Michael J Gibney, Influence of acute phytochemical intake on human urinary metabolomic profiles, The American Journal of Clinical Nutrition, Volume 86, Issue 6, December 2007, Pages 16871693, Cassidy A, Dalais FS

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