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GHK-Cu is present in human plasma, saliva, and urine, with concentrations highest during youth and gradually declining with age

At the same time, the researchers found that lung epithelial cells were surrounded by host immune cells, and the number of macrophages did not increase before and after infection, while the expression level of iNOS increased

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These findings indicate that disrupted iron homeostasis in OA may be more closely related to impaired iron export or excessive uptake, rather than local hepcidin overproduction