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The GAPS diet focuses on healing the gut lining, restoring healthy gut flora, and reducing inflammation to improve overall health and prevent potentially harmful substances from seeping into the bloodstream, affecting brain function and development[139]

The BNST plays a crucial role in regulating anxiety caused by long-term threats, and it is also important in mediating stress-induced anorexia and associated weight loss (298300)

Concurrently, altered glucose metabolism in the orbitofrontal cortex and limbic regions reflects energy deficits and mitochondrial dysfunction, contributing to the severity of psychiatric symptoms, such as paranoia, agitation, and mood disturbances ( MRI studies have further identified gray matter atrophy in the prefrontal cortex, medial cingulate gyrus, and hippocampus, regions that are critically involved in memory, decision-making, and emotional regulation (Thompson et al., 2004)