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For example, Nrf2 activators upregulate endogenous antioxidant defenses and exert neuroprotective, anti-apoptotic effects, while mitophagy modulators promote the selective clearance of dysfunctional mitochondria

one or more nucleotides of the oligonucleotide are linked by non-standard linkages or backbones (e.g., modified internucleoside linkages or modified backbones)

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Sodium butyrate, a HDAC inhibitor, improves sociability in Black and Tan BRachyury (BTBR) T + ltpr3 tf /J mouse models through transcriptional changes in excitatory and inhibitory genes in the prefrontal cortex [92]

10.1182/blood-2013-06-427757 CrossRef Google Scholar View reference in article 35 Meyron-HoltzE