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Irregularity in menstrual cycle Vitamin B12 deficiency can contribute to hormonal imbalances in women, affecting the production of estrogen, progesterone, and even testosterone

Widespread pain was defined as 3 out of 4 quadrant pain, including left- and right-sided and upper- and lower-segment pain, and axial pain

Hormonal Side Effects Artificially elevated testosterone and estrogen levels from hCG in the absence of true deficiency may lead to symptoms like gynecomastia, acne, and emotional volatility in some individuals

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