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Machine perfusion versus cold storage for the preservation of kidneys donated after cardiac death: a multicenter, randomized, controlled trial

(April 2013)

IGF-1 plays a central role in tumor development by stimulating proliferation and inhibiting apoptosis in cancer cells. Pollak, Nature Reviews Cancer Acromegaly-Like Symptoms (Rare) In extremely high or prolonged dosesespecially when stacked with HGHIGF-1 may contribute to: Bone thickening (jaw, forehead, hands) Enlarged soft tissue Headaches or carpal tunnel symptoms These side effects mimic acromegaly , a condition caused by excessive GH/IGF-1 signaling

[Google Scholar] 6.Imperato-McGinley J, Guerrero L, Gautier T, Peterson RE
