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This invaluable substance thus has remarkable liver-related detoxification properties and is responsible for eliminating many 'xenobiotic' (foreign) toxins

The recommended daily intake is 2.3 mg for men and 1.8 mg for women ( Manganese deficiency can present with skin and hair alterations (such as dermatitis, impaired growth of hair and nails, and color changes in hair and beard), nausea and vomiting, ataxia and loss of equilibrium, altered carbohydrate and lipid metabolism, skeletal changes with defects and poor bone formation, impaired reproductive function, and reduced concentrations of clotting proteins (354)

Given the diverse metabolic fates of amino acids and the distinct metabolic demands of cells and tissues throughout the body, it is difficult to estimate which pathways may become limited for a given analyte

doi: 10.1016/s0531-5565(02)00175-4 71 DrgeW