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Recognizing the early signs and symptoms such as fatigue, weakened immune system, and impaired detoxification can help identify and address glutathione deficiency.

Published research has shown that pre-treatment for 72 hours of human promyelocytic leukemia (HL-60)cells with calcitriol or its new analogues significantly potentiated their sensitivity to the antiproliferative effect in vitro of cisplatin, doxorubicin or genistein

It is thought that CpG ODNs mediate TLR9 dimerization in immune cells (e.g., B cells, monocytes and plasmacytoid dendritic cells (pDCs)) to upregulate cytokines (e.g., type I interferon and interleukins), thereby activating natural killer cells

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Three other drugs used clinically against leishmaniasis (meglumine antimoniate [1720], miltefosine [20, 33] and sitamaquine [19, 20, 34]) were not considered in the analysis as they were not present in DrugBank