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Description

Many previous studies have reported evidence of the formation of such glutathionyl quinone or naphthoquinones adducts (31,32) .The C-2 and C-3 in juglone, can react with nucleophiles like glutathione to form adducts

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Several studies had demonstrated that the activity of cytochrome c oxidase (part of a complex enzymatic system in the mitochondria) was significantly lower in AD than normal [196-198]