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[DOI] [PMC free article] [PubMed] [Google Scholar] Bellamine A., Durkee S
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Jun 2014;25(5):471-6
Despite that oxidative stress cab help to this syndrome, the replacement of antioxidants and vitamins is not enough to improve the clinical symptoms of the disease
Here we have identified that depletion of -ketoglutarate (KG) sensitizes HR-proficient cells to DNA-damaging agents by metabolic regulation of histone acetylation
