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Sep2023;15(9):e44852
Small molecule inhibitors targeting key enzymes of lipid synthesisincluding firsocostat (Acetyl-CoA Carboxylase inhibitor), TVB-2640 (Fatty Acid Synthase inhibitor), and aramchol (Stearoyl-CoA Desaturase-1inhibitor) have shown efficacy in reducing hepatic fat accumulation and indirectly attenuating HSC activation

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doi: 10.1016/j.mam.2004.06.003 24

Increase dosage gradually