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Description
The free drug is responsible for tissue toxicity (rather than the total level in the blood)

This result suggests that the therapeutic effects of paliperidone extend beyond its impact on dopamine and serotonin neurotransmission systems (162)

Voineagu I, Wang X, Johnston P, Lowe JK, Tian Y, Horvath S, et al

Chlorophyllin: In patients with leukopenia, chlorophyllin was found to be as effective as a granulocyte-colony stimulating factor medication in the treatment of leukopenia

doi: 10.1016/0022-4731(79)90093-1
