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In terms of biochemical characteristics, cells undergoing ferroptosis show an imbalance of oxidationreduction levels: a significant increase in intracellular reactive oxygen species (ROS) and a significant decrease in NADPH, and therefore lipid antioxidants can inhibit ferroptosis

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There may be an increased risk of severe adverse reactions in elderly patients, particularly when complicating conditions exist, e.g., impaired kidney and/or liver function, or concomitant use of other drugs

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Clinicopathological features and prognosis of papillary thyroid cancer patients with type 2 diabetes mellitus