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Description
Baales-Luna et al
Defyne is the firmer of the two, and works best for deeper placements
Weber AE, Gallo MC, Bolia IK, Cleary EJ, Schroeder TE, Hatch GFR
Thus, as a general understanding, in the context of experimental therapeutics, increasing model complexitycharacterized by the engagement of multiple molecular targets and biological pathwayshas to be associated with a proportional increase in the risk of adverse effects [1]

While less common than flushing, these cardiovascular effects raise understandable concern