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doi: 10.1016/j.neuron.2004.09.012 141 MangoD.SaidiA.CisaleG

Cellular senescence is a state in which cells permanently exit the cell cycle but resist normal apoptotic signaling
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However, it requires multiple injections over the course of a few months to achieve results, and results are irreversible.1 Moreover, bovine collagen gel is an older form of treatment that is not always used at clinic level, and its bovine origin may be incompatible with the beliefs of some patients