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These findings suggest that the peptide may operate as a high-level modulator rather than simply a single-pathway effector, which broadens its appeal for investigations into complex tissue-level phenomena

Moreover, the rate of apoptotic cells was significantly higher in the aging group than in the control group, but it was decreased in the Epitalon-supplemented group (Figure 5D), suggesting that the addition of an appropriate concentration of Epitalon in vitro could reduce the degree of early apoptosis of oocytes

Mayendraraj, A., Rosenkilde, M

FEBS Lett 592:20832097 Wang F, Marshall CB, Yamamoto K, Li GY, Plevin MJ, You H, Mak TW, Ikura M (2008) Biochemical and structural characterization of an intramolecular interaction in FOXO3a and its binding with p53

For example, in the treatment of Alzheimers diseases (AD) and Parkinsons diseases (PD), GLP-1RAs have shown potential in slowing disease progression, while their anti-inflammatory properties offer new hope for conditions such as osteoarthritis (OA), rheumatoid arthritis (RA) and cardiovascular diseases