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Disclaimer: This spotlight is provided for educational purposes to acknowledge scientific contributions to MOTS-c research

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Mechanism of action in the mouth (oral cavity) Wound healing: Stimulates fibroblast activity, collagen synthesis, and keratinocyte migration, accelerating soft tissue repair (important for periodontal disease, oral ulcers, or mucosal trauma) 2 Anti-inflammatory modulation Reduces neutrophil and macrophage overactivation, limiting collateral damage to gum tissue 3 : Bone and ligament support: Early studies suggest BPC-157 promotes tendon-to-bone healing and osteogenesis, potentially relevant for periodontitis-related bone loss or implant integration