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A phase 2 randomised controlled trial published in the New England Journal of Medicine (2023) reported substantial weight loss and improvements in glycaemic parameters, though the trial was conducted in a closely monitored clinical setting with defined eligibility criteria
No regulatory approvals exist for this indication

Data distribution was analyzed using Anderson-Darling, DAgostino & Person, Shapiro-Wilk and Kolmogorov-Smirnov tests

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